Born in Madrid, Alfonso González Barquín studied in Spain with José Miguel Sambartolomé and Luis González, and in Germany with Reinhold Friedrich and Laura Vukobratovic. He further refined his skills in France with Pierre Thibaud and in the United States with Thomas Hooten.
During his studies, he was a member of the National Youth Orchestra of Spain and the Ibero-American Youth Orchestra under Gustavo Dudamel, and, as a fellow, of the Düsseldorf Symphony Orchestra.
Alfonso has performed with the Orchestra Mozart of Bologna under Claudio Abbado and with the West-Eastern Divan Orchestra conducted by Daniel Barenboim. He has served as principal trumpet with numerous ensembles, including the Duisburger Philharmoniker, the National Theatre Mannheim Orchestra, the Royal Concertgebouw Orchestra, the Rotterdam Philharmonic, the Royal Scottish National Orchestra, the National Orchestra of Belgium, the KBS Symphony Orchestra in Seoul, and the Freiburg Baroque Orchestra.
He was principal trumpet of the Brussels Philharmonic and, since 2018, holds the same position with the Orchestra of the Accademia Nazionale di Santa Cecilia in Rome. Alfonso also teaches at the Musikene Higher Conservatory of Music in San Sebastián, Spain.